Knowledge, Attitude, Practices, and Barriers of Pharmacovigilance among Healthcare Workers

Abstract

Background: Pharmacovigilance plays a critical role in drug safety, yet underreporting of adverse drug reactions (ADRs) remains a global challenge, particularly in low- and middle-income countries. This study assessed the knowledge, attitudes, and practices (KAP) of healthcare professionals (HCPs) in Libya regarding pharmacovigilance and ADR reporting.

Methods: A cross-sectional survey was conducted among 120 doctors, pharmacists, and nurses in Libya using a structured questionnaire. Convenience sampling was employed due to accessibility constraints. The questionnaire covered demographic data, knowledge of pharmacovigilance, attitudes toward ADR reporting, and self-reported practices. Descriptive statistics were used to analyze responses.

Results: The majority of participants were young (75% under 30 years), female (90%), and pharmacists (60%), with limited work experience (65% ≤3 years). Only 55% correctly defined pharmacovigilance, and 70% were unaware of the WHO Collaborating Centre’s location (Sweden). While 60% were willing to report ADRs, key barriers included limited awareness (65%) and time constraints (50%). Despite 70% having identified an ADR, only 40% had reported one, highlighting a significant gap between detection and reporting.

Conclusion: Significant knowledge gaps and systemic barriers hinder effective ADR reporting among Libyan HCPs. Targeted educational interventions, simplified reporting mechanisms, and institutional support are needed to strengthen pharmacovigilance practices in Libya.